Will new Chaintech MB work with old drives?

I am about to replace my DFI MB with a Chaintech S1689 AMD Motherboard.

But, I have one question, will the drivers for the DFI interfear with the S
1689?

Or, to put it another way, if I install the S1869, hook it up to the same
hard drive(s) that I used on the DFI, and turn it on, will the S1869 work?

At lease to the point that I can install its drivers?

And should I (and at what point) remove (if I can find them) the old DFI
drivers?